谢道昕
谢道昕,教授,博导,长江学者特聘教授,国家杰出青年基金获得者,现任清华大学植物分子生物学实验室主任。
中文名:谢道昕
国籍:中国
民族:汉族
职业:植物分子生物学教授
毕业院校:湖南农学院
1、人物简介
教授,博士生导师,教育部长江学者特聘教授,国家杰出青年基金获得者,ScienceChinaLifeSciences,JIPB,MolecularPlant和ThePlantJournal等学术期刊编委。
2、人物履历
2006-现在:清华大学(“百人计划”责任教授)
2002-2006:新加坡分子细胞生物所(实验室主任,资深科学家)
1999-2002:新加坡国立大学农业分子生物所(实验室主任,助理教授)
1994-1999:英国EastAnglia大学(SeniorResearchAssociate)
1990-1994:英国JohnInnes研究中心和英国Leicester大学(ResearchAssociate)
1984-1990:中国农科院研究生院(MSc.,Ph.D.)
1983-1984:湖南棉花科学研究所(ResearchAssistant)
1979-1983:湖南农学院(BSc.)
2016年6月12日,谢道昕当选第五届农业转基因生物安全委员会委员。
3、科研领域
激素对于生物的生长发育、新陈代谢和繁衍生息等各种生命活动起重要调节作用;阐明激素的受体识别机制,对于揭示生命现象的本质、提高生物的生存和发展能力具有重要意义。谢道昕实验室主要研究激素感知及其调控植物生长发育和防御反应的分子机制,迄今阐明了茉莉素和独脚金内酯两类激素的受体识别机制:2009年发现的茉莉素受体COI1,遵循生物学领域经典的激素活性分子可逆地结合受体并循环触发信号传导链的“活性分子-受体”识别规律、调控植物的防御反应和生长发育;2016年阐明的独脚金内酯受体D14,则具有生成激素活性分子和不可逆地结合激素活性分子的双重功能、遵循新型的“底物-酶-活性分子-受体”识别规律、调控植物分枝等重要生长发育过程。
4、学术著作
1.YaoR,WangF,MingZ,DuX,ChenL,WangY,ZhangW,DengH,XieD.(2016)ShHTL7isanon-canonicalreceptorforstrigolactonesinrootparasiticweeds.CellResearch(inpress).
2.WuD,QiT,LiW,TianH,GaoH,WangJ,GeJ,YaoR,RenC,WangX,LiuY,KangL,DingS,XieD.(2016)Viraleffectorproteinmanipulateshostjasmonatesignalingtoattractinsectvectors.CellResearch(inpress).
3.YaoR,MingZ,YanL,LiS,WangF,MaS,YuC,YangM,ChenL,ChenL,LiY,YanC,MiaoD,SunZ,YanJ,SunY,WangL,ChuJ,FanS,HeW,DengH,NanF,LiJ,RaoZ,LouZandXieD.(2016)DWARF14isanon-canonicalhormonereceptorforstrigolactone.Nature536:469-73.(FeaturedinNatureandScienceSignaling)
4.QiT,WangJ,HuangH,LiuB,GaoH,LiuY,SongS,XieD.(2015)RegulationofJasmonate-InducedLeafSenescencebyAntagonismbetweenbHLHSubgroupIIIeandIIIdFactorsinArabidopsis.PlantCell27:1634-49.
5.QiT,HuangH,SongSandXieD.(2015)ControlofJasmonate-regulatedStamenDevelopmentandSeedProductionbyabHLH-MYBComplexinArabidopsis.PlantCell27:1620-33.
6.QiT,HuangH,WuD,YanJ,QiY,SongSandXieD.(2014).ArabidopsisDELLAandJAZProteinsBindtheWD-repeat/bHLH/MYBComplextoModulateGibberellinandJasmonateSignalingSynergy.PlantCell26:1118-33.
7.SongS,HuangH,GaoH,WangJ,WuD,LiuX,YangS,ZhaiQ,LiC,QiTandXieD.(2014)InteractionofMYC2withEIN3ModulatesAntagonismbetweenJasmonateandEthyleneSignaling.PlantCell26:263-79.
8.HuP,ZhouW,ChengZ,FanM,WangLandXieD.(2013)JAV1controlsJasmonate-regulatedplantdefense.MolecularCell50:504-15(coverstory;featuredinMol.Cell)
9.SongS,QiT,WasternackC.andXieD.(2014).Jasmonatesignalingandcrosstalkwithgibberellinandethylene.CurrentOpinioninPlantBiology21C:112-119.
10.YanJ.,LiH.,LiS.,YaoR,DengH.,XieQ.andXieD.(2013)TheArabidopsisF-boxproteinCORONATINEINSENSITIVE1isstabilizedbySCFCOI1anddegradedviathe26Sproteasomepathway.PlantCell25:486-98.(recommendedbyFaculty1000)
11.SongS,QiT,FanM,ZhangX,GaoH,HuangH,WuD,GuoH,XieD.(2013)ThebHLHSubgroupIIIdFactorsNegativelyRegulateJasmonate-mediatedPlantDefenseandDevelopment.PLoSGenetics9,e1003653.
12.QiT,SongS,RenQ,WuD,HuangH,ChenY,FanM,PengW,RenCandXieD.(2011)TheJasmonate-ZIM-domainProteinsInteractwiththeWD-repeat/bHLH/MYBComplexestoControlJasmonate-regulatedAnthocyaninAccumulationandTrichomeInitiationinArabidopsis.PlantCell23:1795-814.
13.ShanX,YanJ,XieD.(2012)Comparisonofphytohormonesignalingmechanisms.CurrentOpinioninPlantBiology15(1):84-91.
14.SongS,QiT,HuangH,RenQ,WuD,ChangC,PengW,LiuY,PengJandXieD.(2011)TheJasmonate-ZIM-domainProteinsInteractwiththeR2R3-MYBTranscriptionFactorsMYB21andMYB24toControlJasmonate-regulatedStamenDevelopmentinArabidopsis.PlantCell23:1000-13.
15.YanJ,ZhangC,GuM,BaiZ,ZhangW,QiT,ChengZ,PengW,LuoH,NanF,WangZ,XieD.(2009)TheArabidopsisCORONATINEINSENSITIVE1proteinisajasmonatereceptor.PlantCell21:2220-36(recommendedbyFaculty1000,featuredinNat.Chem.Bio.andPlantCell)
16.ChengH,SongS,XiaoL,SooH,ChengZ,XieDandPengJ.(2009)GibberellinActsThroughJasmonatetoControltheExpressionofMYB21,MYB24andMYB57toPromoteStamenFilamentGrowthinArabidopsis.PLoSGenetics5(3):e1000440.
17.TanL,LiX,LiuF,SunX,LiC,ZhuZ,FuY,CaiH,WangX,XieDandSunC.(2008)Controlofakeytransitionfromprostratetoerectgrowthinricedomestication.NatureGenetics40:1360-4.
18.XiaoS,DaiL,LiuL,WangZ,PengW,XieD.(2004)COS1:anArabidopsiscoi1suppressoressentialforregulationofjasmonate-mediatedplantdefenseandsenescence.PlantCell16:1132-42.
19.LiuF,NiW,GriffithME,HuangZ,ChangC,PengW,MaHandXieD.(2004)TheASK1andASK2GenesAreEssentialforArabidopsisEarlyDevelopment.PlantCell16:5-20.
20.XuL,LiuF,LechnerE,GenschikP,CrosbyWL,MaH,PengW,HuangDandXieD.(2002)TheSCF(COI1)ubiquitin-ligasecomplexesarerequiredforjasmonateresponseinArabidopsis.PlantCell14:1919-35.
21.XieD,FeysF,JamesS,Nieto-RostroMandTurnerJ.(1998)COI1:anArabidopsisgenerequiredforjasmonate-regulateddefenseandfertility.Science280:1091-4.
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